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Natural and Designer Steroids and Human Androgen Receptor
Human Androgen Receptor and Testosterone
(based on 2AM9.pdb)
Androgen backbone and spacefilled steroid
Steroid (testosterone) Only Steroid (testosterone) Only in CPK colors
Hydrogen bonding between receptor and steroid (cyan)
London dispersion forces between hydrophobic components (orange)
Additional London dispersion forces between hydrophobic components in THG (yellow)
Combined forces holding steroid in the androgen receptor
Combined forces holding steroid in the androgen receptor without backbone shown
Androgen backbone and spacefilled steroid
Steroid (testosterone) Only Steroid (testosterone) Only in CPK colors
Hydrogen bonding between receptor and steroid (cyan)
London dispersion forces between hydrophobic components (orange)
Additional London dispersion forces between hydrophobic components in THG (yellow)
Combined forces holding steroid in the androgen receptor
Combined forces holding steroid in the androgen receptor without backbone shown
Human Androgen Receptor and THG
(based on 2AMB.pdb)
Turn on spin for testosterone in receptor.
Turn on spin for synthetic steroid in receptor.
Turn on spin for testosterone in receptor.
Turn on spin for synthetic steroid in receptor.